International Symposium

5th International Symposium of the TRR259

It is with great pleasure that we invite you to join our 5th International Symposium of the Collaborative Research Center/Transregio TRR 259 on “New mechanistic insights into aortic diseases. From molecular mechanisms to clinical applications.“, which will take place from April 07 – 09, 2025 in Bonn, Germany.

The TRR259 is a Collaborative Research Center funded by the German Research Foundation (DFG) at the Universitites of Bonn, Cologne, and Düsseldorf. In a multidisciplinary effort, we are investigating the molecular and cellular mechanisms of aortic disease holistically, with a particular focus on aortic valve stenosis, aortic
aneurysm, and aortic dissection. We aim to identify novel pharmacological, interventional, and surgical targets for new diagnostic, preventive, and
therapeutic strategies within the frame of translational and clinical studies.

For the 5th International Symposium of the TRR259 in 2025, world-class scientists, clinicians, and students, will share their experiences and results of research into the basic mechanisms of the development of aortic wall and valve disease. The International Symposium 2025 will not only showcase the latest research data, but also foster discussion and interaction between aortic researchers, and will be a unique opportunity to initiate and intensify collaborative projects. The theme of this event will be “New mechanistic insights into aortic diseases”.

We look forward to welcoming you in Bonn for this exciting conference on aortic diseases!

Deadlines

Registration for on-site participation: February 1, 2025

Abstract Deadline for Poster Session: March 7, 2025

Registration for on-site participation

Abstract submission for Poster Session (TRR259 members only)

Program

Find out more about the program of the 3rd International Symposium in Bonn

Program

Speakers

Here you will find a list of the speakers who have already agreed to join the symposium

Speakers

Poster Session

Here you will find further information about the poster session of TRR259 members and how to submit an abstract

Poster Session

Travel information

Find more information here about your arrival and departure options, as well as possible accomodation

Travel information

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Participants

Plenary Lectures

Poster Session

Conference Highlights

Modulation of extracellular matrix

Anders Wanhainen (Uppsala, SE) • Bernard M. van den Berg (Leiden, NL) • Philip S. Tsao (Stanford, US) • Anand Ramamurthi (Bethlehem, US) • Bart Loeys (Antwerp, BE)

Cell characterization and communication

Bernard D. Prendergast (London, UK) • Joost Sluijter (Utrecht, NL) • Rafael Kramann (Aachen, DE) • Alessandra Moretti (Munich, DE) • Stefanie Dimmeler (Frankfurt, DE) • Marc Beyer (Bonn, DE)

Immunometabolism

Musa Mhlanga (Nijmegen, NL) • Matthias Blüher (Leipzig, DE) • Terje Espevik (Trondheim, SE) • Mark Febbraio (Melbourne, AU) • Michael Roden (Düsseldorf, DE) • Magnus Bäck (Karolinska, SE)

Immunological mechanisms

Niels Riksen (Nijmegen, NL) • Dominik Wolf (Innsbruck, AT) • • Alma Zernecke-Madsen (Würzburg, DE) • Takashi Fujita (Kyoto, JAP) • Filip Swirski (New York, US)

Translation into therapies

Lars Maegedefessel (Munich, DE) • Artur Lichtenberg (Düsseldorf, DE) • Christian Weber (Munich, DE)