Over the next four years, we will build upon our previous work and initiate new projects to further our understanding of the underlying causes and potential treatments for aortic diseases. We are incredibly grateful to the DFG for their continued support, and we look forward to sharing our progress with the scientific community and beyond.
As part of our extended funding, we are thrilled to welcome several new project leaders who will be spearheading exciting new research projects within the TRR259. Each of these projects has been carefully selected to address key knowledge gaps in the field of aortic diseases and build upon our previous successes.
Allow us to introduce our new project leaders:
A05: Welcome Dr. Susanne Schmidt (Institute of Innate Immunity, Bonn)
A08: Welcome Dr. Staffan Hildebrand (Institute of Pharmacology and Toxicology, Bonn)
B04: Welcome Dr. Mohammed Rabiul Hosen (Department of Internal Medicine II, Heart Centre Bonn) and Philip Roger Goody (Department of Internal Medicine II, Heart Centre Bonn)
B05: Welcome Prof. Ana García-Sáez (Institute for Genetics, Cologne)
C05: Welcome Prof. Maximilian Billmann (Institute of Human Genetics, Bonn)
MGK: Welcome Prof. Ute Mons (Clinic III for Internal Medicine, Cologne)
Allow us to introduce our new project leaders and their exciting research projects:
A09: “The role of the olfactory receptor 2 in aortic aneurysm formation”, Prof. Holger Winkels (Clinic III for Internal Medicine)
B10: “Sphingosine-1-phosphate (S1P) signalling in aortic aneurysm formation and dissection”, Prof. Bodo Levkau (Department of Molecular Medicine III)
C01: “Modelling of cardiac valve and aortic aneurysm diseases using human induced pluripotent stem cells (hiPSCs)”, Prof. Bernd Fleischmann and Dr. Sarah Rieck (Institute of Physiology I, Bonn)
C02: “The role of local and systemic haemodynamic forces and inflammatory patterns in the development of aortic disease”, Prof. Ulrich Flögel (Department of Molecular Cardiology, Düseldorf), PD Dr. Florian Bönner (Department of Cardiology, Pneumology and Vascular Medicine, Düsseldorf), Prof. Verena Hörr (Department of Internal Medicine II, Heart Centre Bonn)
C03: “The impact of nitrated fatty acids in a translational porcine model of abdominal aortic aneurysm”, Dr. Martin Mollenhauer (Clinic III for Internal Medicine, Cologne), Dr. Marta Stei (Department of Internal Medicine II, Heart Centre Bonn), PD Dr. Markus Wagenhäuser (Department of Vascular and Endovascular Surgery, Düsseldorf)
C04: “Characterising the innate immune response to decellularised extracellular matrix-based heart valve and aortic implants”, PD Dr. Hug Aubin (Department of Cardiovascular Surgery), Prof. Eva Bartok (Institute of Experimental Haematology and Transfusion Medicine)
C06: “Biomarkers and mechanisms of disease progression and outcome in aortic stenosis in humans“, Prof. Bernardo Franklin (Institute of Innate Immunity, Bonn), PD Dr. Julian Luetkens (Department of Diagnostic and Interventional Radiology, Bonn), Dr. Victor Mauri (Clinic III for Internal Medicine, Cologne), Dr. Jasmin Shamekhi (Department of Internal Medicine II, Heart Centre Bonn), PD Dr. Verena Veulemans (Department of Cardiology, Pneumology and Vascular Medicine, Düsseldorf)
S02: “Transcriptomics and epigenetic data analysis“, Prof. Maximilian Billmann (Institute of Human Genetics, Bonn), Dr. Susanne Schmidt (Institute of Innate Immunity, Bonn)