S02-Transcriptomics and epigenetic data analysis
The bioinformatics platform will support the research projects of the consortium in planning of experimental setups, analysis, manuscript preparation and publication of next-generation sequencing (NGS) data. Multiple projects have already or will generate bulk and/or single-cell sequencing datasets of mRNA, epigenetic changes in histone modifications as well as accessible chromatin regions (ATAC sequencing), which will be analysed by the researchers of the bioinformatics platform. Using a diverse set of statistical tools and machine learning algorithms, the platform will also perform analysis of CRISPR-based functional screens and data mining by integration of clinical, proteomics and sequencing data to develop novel data-driven research approaches.
![Bioinformatics Platform S02 overview.png](https://www.trr259.uni-bonn.de/en/bilder-trr259/2-funding-period-projektubersichten/bioinformatics-platform-s02-overview.png/@@images/image/large)
Contacts
Dr. Susanne Schmidt
Building 24, 1st floor, room 041
Institute of Clinical Chemistry and Clinical Pharmacology
AG Immune Monitoring & Genomics
University Hospital Bonn
Venusberg-Campus 1
53127 Bonn
Jun.-Prof. Dr. Maximilian Billmann
Building 76
Institute of Human Genetics
University Hospital Bonn
Venusberg-Campus 1
53127 Bonn
Jasper Spitzer
Building 24
Institute of Clinical Chemistry and Clinical Pharmacology
AG Immune Monitoring & Genomics
University Hospital Bonn
Venusberg-Campus 1
53127 Bonn