TRR259 - Aortic Disease
University of Bonn
TRR259 - Aortic Disease
University of Cologne
TRR259 - Aortic Disease
University of Düsseldorf
TRR259 - Aortic Disease
TRR259 - Aortic Disease
TRR259 - Aortic Disease

Publications of the TRR259 - 2020

Quantification of Lipoprotein Uptake in Vivo Using Magnetic Particle Imaging and Spectroscopy

Hildebrand, Staffan, Norbert Löwa, Hendrik Paysen, Raluca M. Fratila, Laia Reverte-Salisa, Thithawat Trakoolwilaiwan, Zheming Niu, Georgios Kasparis, Stephanie Franziska Preuss, Olaf Kosch, Jesus M. de la Fuente, Nguyen Thi Kim Thanh, Frank Wiekhorst, and Alexander Pfeifer.

2020 Dec 11.  ACS Nano. doi: 10.1021/acsnano.0c03229.

Vaccination in Atherosclerosis 

Felix Sebastian Nettersheim, Lauren De Vore and Holger Winkels

Cells 2020,Nov 30, 9, 2560, https://doi.org/10.3390/cells9122560

MicroRNA-mediated vascular intercellular communication is altered in chronic kidney disease

Andreas Zietzer; Eva Steffen; Sven Niepmann; Philip Düsing; Mohammed Rabiul Hosen; Weiyi Liu; Paul Jamme; Baravan Al-Kassou; Philipp Roger Goody; Sebastian Zimmer; Katrin S Reiners; Alexander Pfeifer; Michael Böhm; Nikos Werner; Georg Nickenig; Felix Jansen,

Cardiovascular Research cvaa322, 2020 Nov. 02, https://doi.org/10.1093/cvr/cvaa322

Reelin Amplifies Glycoprotein VI Activation and AlphaIIb Beta3 Integrin Outside-In Signaling via PLC Gamma 2 and Rho GTPases

Krueger, Irena, Lothar Gremer, Lena Mangels, Meike Klier, Kerstin Jurk, Dieter Willbold, Hans H. Bock, and Margitta Elvers 

Arteriosclerosis, Thrombosis, and Vascular Biology, 2020 Oct, 40(10):2391–2403. doi: 10.1161/ATVBAHA.120.314902. 

Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits

Marina A. Heuschkel, Nikolaos T. Skenteris, Joshua D. Hutcheson, Dewy D. van der Valk, Juliane Bremer, Philip Goody, Jesper Hjortnaes, Felix Jansen, Carlijn V.C. Bouten, Antoon van den Bogaerdt, Ljubica Matic,
Nikolaus Marx and Claudia Goettsch

Cells 2020 Sep 24, 9(10), 2164; https://doi.org/10.3390/cells9102164

Pulmonary hypertension associated with left-sided heart failure

Adler J, Gerhardt F, Wissmüller M, Adler C, Baldus S, Rosenkranz S.

Curr Opin Cardiol. 2020 Sep 21. doi: 10.1097/HCO.0000000000000791. Epub ahead of print. PMID: 32969856

Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis

Mollenhauer M, Mehrkens D, Klinke A, Lange M, Remane L, Friedrichs K, Braumann S, Geißen S, Simsekyilmaz S, Nettersheim FS, Lee S, Peinkofer G, Geisler AC, Geis B, Schwoerer AP, Carrier L, Freeman BA, Dewenter M, Luo X, El-Armouche A, Wagner M, Adam M, Baldus S, Rudolph V. 

Sci Rep. 2020 Sep 18;10(1):15319. doi: 10.1038/s41598-020-71870-6. PMID: 32948795; PMCID: PMC7501300.

Hyperlipidemia does not affect development of elastase-induced abdominal aortic aneurysm in mice

Joscha Mulorz, Joshua Michael Spin, Hans Christian Beck, My Linh Tha Thi, Markus Udo Wagenhäuser, Lars Melholt Rasmussen, Jes Sanddal Lindholt, Philip Shih Chung Tsao, Lasse Bach Steffensen

Atherosclerosis, 2020 Aug 29, Volume 311, 73 – 83, https://doi.org/10.1016/j.atherosclerosis.2020.08.012

Nitro-fatty acids suppress ischemic ventricular arrhythmias by preserving calcium homeostasis

Mollenhauer M, Mehrkens D, Klinke A, Lange M, Remane L, Friedrichs K, Braumann S, Geißen S, Simsekyilmaz S, Nettersheim FS, Lee S, Peinkofer G, Geisler AC, Geis B, Schwoerer AP, Carrier L, Freeman BA, Dewenter M, Luo X, El-Armouche A, Wagner M, Adam M, Baldus S, Rudolph V.

Sci Rep. 2020 Sep 18;10(1):15319. doi: 10.1038/s41598-020-71870-6. PMID: 32948795.

Risk modeling in transcatheter aortic valve replacement remains unsolved: an external validation study in 2946 German patients.

Wolff G, Shamekhi J, Al-Kassou B, Tabata N, Parco C, Klein K, Maier O, Sedaghat A, Polzin A, Sugiura A, Jung C, Grube E, Westenfeld R, Icks A, Zeus T, Sinning JM, Baldus S, Nickenig G, Kelm M, Veulemans V. 

Clin Res Cardiol. 2020 Aug 26. doi: 10.1007/s00392-020-01731-9. Epub ahead of print. PMID: 32851491.

Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas

Zernecke, Alma, Holger Winkels, Clément Cochain, Jesse W. Williams, Dennis Wolf, Oliver Soehnlein, Clint S. Robbins, Claudia Monaco, Inhye Park, Coleen A. McNamara, Christoph J. Binder, Myron I. Cybulsky, Corey A. Scipione, Catherine C. Hedrick, Elena V. Galkina, Tin Kyaw, Yanal Ghosheh, Huy Q. Dinh, and Klaus Ley

Circulation Research, 2020 Jul 16, 127(3):402–26. doi: 10.1161/CIRCRESAHA.120.316903

The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles

Andreas Zietzer, Mohammed Rabiul Hosen, Han Wang, Philip Roger Goody, Marc Sylvester, Eicke Latz, Georg Nickenig, Nikos Werner & Felix Jansen

Journal of Extracellular Vesicles 2020 Jul 02, 9:1, 1786967, DOI: 10.1080/20013078.2020.1786967

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

Thorsten Gnad, Gemma Navarro, Minna Lahesmaa, Laia Reverte-Salisa, Francesca Copperi, Arnau Cordomi, Jennifer Naumann, Aileen Hochhäuser, Saskia Haufs-Brusberg, Daniela Wenzel, Frank Suhr, Naja Zenius Jespersen, Camilla Scheele, Volodymyr Tsvilovskyy, Christian Brinkmann, Joern Rittweger, Christian Dani, Mathias Kranz, Winnie Deuther-Conrad, Holger K. Eltzschig, Tarja Niemi, Markku Taittonen, Peter Brust, Pirjo Nuutila, Leonardo Pardo, Bernd K. Fleischmann, Matthias Blüher, Rafael Franco, Wilhelm Bloch, Kirsi A. Virtanen, Alexander Pfeifer

Cell Metabolism, 2020 June; https://doi.org/10.1016/j.cmet.2020.06.006

Sustained Immunoparalysis in Endotoxin-Tolerized Monocytic Cells

Christina K. Weisheit, Alexandra Klüners, Lennart Wild, Alexandra Casalter, Stefanie Heilmann-Heimbach, Sugirthan Sivalingam, Jan L. Kleiner, Stefan F. Ehrentraut, Andreas Hoeft, Stilla Frede, and Heidi Ehrentraut

Mediators of Inflammation, 2020 Jun 13, https://doi.org/10.1155/2020/8294342

MicroRNAs As Master Regulators of Atherosclerosis: From Pathogenesis to Novel Therapeutic Options

Mohammed Rabiul Hosen, Philip Roger Goody, Andreas Zietzer, Georg Nickenig, and Felix Jansen

Antioxidants & Redox Signaling 2020 June; https://doi.org/10.1089/ars.2020.8107

Hot spot 19F magnetic resonance imaging of inflammation

Pascal Bouvain, Sebastian Temme, Ulrich Flögel

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2020 [published online ahead of print, 2020 May 7].e1639.doi:10.1002/wnan.1639

Basic Biology of Extracellular Matrix in the Cardiovascular System, Part 1/4: JACC Focus Seminar

del Monte-Nieto, Gonzalo, Jens W. Fischer, Daniel J. Gorski, Richard P. Harvey, and Jason C. Kovacic

 Journal of the American College of Cardiology, 2020 May 5, 75(17):2169–88.doi: https://doi.org/10.1016/j.jacc.2020.03.024.

Thymic stromal lymphopoietin is a key cytokine for the immunomodulation of atherogenesis with Freund's adjuvant

Martin Steinmetz, Ludivine Laurans, Sarah Nordsiek, Lena Weiß, Bieke van der Veken, Padmapriya Ponnuswamy, Bruno Esposito, Marie Vandestienne, Andreas Giraud, Cristina Göbbel, Eva Steffen, Tobias Radecke, Stephane Potteaux, Georg Nickenig, Tienush Rassaf, Alain Tedgui, Ziad Mallat

Journal of Cellular and Molecular Medicine 2020 May;24(10) 5731-5739; DOI: 10.1111/jcmm.15235, PMID: 32285594

Basic Biology of Extracellular Matrix in the Cardiovascular System

Del Monte-Nieto G, Fischer JW, Gorski DJ, Harvey RP, Kovacic JC.

Part 1/4 JACC Focus Seminar. J Am Coll Cardiol. 2020 May, 75 (17) 2169–2188 doi:10.1016/j.jacc.2020.03.024 

New Insights into the Regulation of Apoptosis, Necroptosis, and Pyroptosis by Receptor Interacting Protein Kinase 1 and Caspase-8

Robin Schwarzer, Lucie Laurien, and Manolis Pasparakis

Current Opinion in Cell Biology, 2020 April, 63:186–93. https://doi.org/10.1016/j.ceb.2020.02.004

In vivo detection of programmed cell death during mouse heart development

Kristel Martínez-Lagunas, Yoshifumi Yamaguchi, Cora Becker, Caroline Geisen, Marco C. DeRuiter, Masayuki Miura, Bernd K. Fleischmann and Michael Hesse

Cell Death & Differentiation 2020 Apr; 27(4):1398-1414, DOI: 10.1038/s41418-019-0426-2, PMID: 31570857

Aortic Valve Stenosis – From Basic Mechanisms to Novel Therapeutic Targets

Philip Roger Goody, Mohammed Rabiul Hosen, Dominik Christmann, Sven Thomas Niepmann, Andreas Zietzer, Matti Adam, Florian Bönner, Sebastian Zimmer, Georg Nickenig, Felix Jansen

Arteriosclerosis, Thrombosis, and Vascular Biology 2020 Apr;40(4):885–900; DOI: 10.1161/ATVBAHA.119.313067, PMID: 32160774

A high-salt diet compromises antibacterial neutrophil responses through hormonal perturbation

Jobin K, Stumpf NE, Schwab S, Eichler M, Neubert P, Rauh M, Adamowski M, Babyak O, Hinze D, Sivalingam S, Weisheit C, Hochheiser K, Schmidt SV, Meissner M, Garbi N, Abdullah Z, Wenzel U, Hölzel M, Jantsch J, Kurts C

Sci Transl Med. 2020 Mar 25;12(536):eaay3850. doi: 10.1126/scitranslmed.aay3850.

High-Sensitivity Troponin T Testing: Consequences on Daily Clinical Practice and Effects on Diagnosis of Myocardial Infarction

Christian Frédéric Zachoval, Ramona Dolscheid-Pommerich, Ingo Graeff, Bernd Goldschmidt, Andreas Grigull, Birgit Stoffel-Wagner, Georg Nickenig, Sebastian Zimmer 

J Clin Med. 2020 Mar 12;9(3):775. doi: 10.3390/jcm9030775. PMCID: PMC7141275

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